Interaction of Immune and Cancer Cells

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Klink, Magdalena (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Vienna : Springer Vienna : Imprint: Springer, 2014.
• Θέματα: Medicine.; Cancer research.; Immunology.; Vaccines.; Molecular biology.; Cytokines.; Growth factors.; Biomedicine.; Cancer Research.; Vaccine.; Cytokines and Growth Factors.; Molecular Medicine.

The tumor environment is a dynamic network that includes cancer cells, immune cells, fibroblasts, endothelial cells, extracellular matrix, cytokines and receptors. The aim of this book is to summarize the role of these components, especially immune cells, in tumor suppression and/or progression and...

Πίνακας περιεχομένων:

• Immune cells within tumor microenvironment
• Tumor-stroma interaction and cancer progression
• The role of tumor associated macrophages (TAMs) in tumor progression
• Dendritic cells dysfunction and tumor progression
• Myeloid-derived suppressor cells (MDSC) and tumor growth
• Tumor-infiltrating lymphocytes and their role in solid tumor progression
• Polymorphonuclear neutrophils and tumor: friend or foe?
• Cancer immunosurveillance and immunoediting
• Adoptive T cell immunotherapy – Perfecting self-defense
• Monoclonal antibodies to CTLA4 with focus on ipilimumab.