The Intervertebral Disc Molecular and Structural Studies of the Disc in Health and Disease /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Shapiro, Irving M. (Επιμελητής έκδοσης), Risbud, Makarand V. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Vienna : Springer Vienna : Imprint: Springer, 2014.
• Θέματα: Medicine.; Neurosurgery.; Orthopedics.; Medicine & Public Health.; Surgical Orthopedics.

The intervertebral disc is composed of a complex tissue that separates neighboring vertebrae, permits a wide range of motion, and cushions the high biomechanical forces on the spine. Disc degeneration leads to a loss of function and is often associated with excruciating pain. Written by leading scie...

Πίνακας περιεχομένων:

• Biomechanical and Molecular Studies of the Intervertebral Disc: Introduction to the Structure, Function and Comparative Anatomy of the Vertebrae and the Intervertebral Disc
• The Intervertebral Disc: Overview of Disc Mechanics
• Development of the Intervertebral Disc
• Proteoglycans of the Intervertebral Disc
• Collagen and Other Proteins of the Nucleus Pulposus, Annulus Fibrosus and Cartilage Endplates
• Microenvironmental Regulation of Cell Function and Extracellular Matrix Synthesis by Disc Cells
• The Effects of Mechanical Forces on Nucleus and Annulus Cells
• The Role of the ADAMTS Proteins in the Intervertebral Disc
• Intervertebral Disc Disease: Pathogenesis and Current Treatment Modalities: Epidemiology of Lumbar Disc Degeneration
• Genetic Basis of Intervertebral Disc Degeneration
• Pathogenesis of Intervertebral Disc Degeneration
• Imaging Modalities for Studying Disc Pathology
• Surgical Indications for Lumbar Degenerative Disease
• Spinal Motion Restoration Devices for the Degenerate Disc
• The Non-Surgical Treatment of Back Pain
• Back Pain and Disc Degeneration: Are They Linked?- Clinical Features and Pathobiology of Chordoma
• Models of Disc Disease and Biological Regeneration: Large Animal Models of Disc Degeneration
• Intervertebral Disc Herniation
• The Sand Rat (Psammomys obesus obesus) Model of Spontaneous, Age-Related Intervertebral Disc Generation
• Use of Knockout and Transgenic Mouse Models in Disc Research
• Intervertebral Disc Culture Models and Their Applications to Study Pathogenesis and Repair
• Use of Stem Cells to Regenerate the Disc
• Gene Therapy Approaches for Disc Regeneration
• Enhancing Disc Repair by Growth Factors and Other Modalities
• Tissue Engineering of the Disc.