The Grand Challenge for the Future Vaccines for Poverty-Related Diseases from Bench to Field /

The most urgently needed vaccines are those against poverty-related diseases such as tuberculosis, malaria and HIV. However, there is a considerable gap between the development of a vaccine and the implementation as a useful measure for disease control. Major obstacles need to be overcome even after...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Kaufmann, Stefan H.E (Επιμελητής έκδοσης), Lambert, Paul-Henri (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Basel : Birkhäuser Basel, 2005.
Σειρά:Birkhäuser Advances in Infectious Diseases BAID
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Background
  • Economic aspects of vaccines and vaccination: a global perspective
  • Private hand
  • How and why vaccines are made
  • How can the industrial world help to implement new vaccines against poverty-related diseases?
  • Public-private partnerships
  • New approaches towards development, production and use of developing-country market vaccines in developing countries
  • Bench
  • Novel vaccination strategies
  • Design and selection of vaccine adjuvants: principles and practice
  • Vaccination in the context of immunological immaturity
  • Regulatory issues
  • Regulatory issues in the development of new vaccines with a special emphasis on safety aspects
  • Clinical trials
  • Clinical trials in developing countries: ethical issues
  • Vaccine safety and adverse events: lessons learnt
  • Sequential stages of clinical trials and overview of issues to be considered
  • Practical aspects of phase 3 vaccine trials in developing countries
  • Vaccination programmes
  • Issues to be considered for the introduction of new vaccines into national vaccination programmes.