Introduction to Computational Biology An Evolutionary Approach /

• Main Authors: Haubold, Bernhard (Author), Wiehe, Thomas (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Basel : Birkhäuser Basel, 2006.
• Subjects: Life sciences.; Computers.; Bioinformatics.; Cell biology.; Evolutionary biology.; Biomathematics.; Life Sciences.; Life Sciences, general.; Theory of Computation.; Evolutionary Biology.; Cell Biology.; Genetics and Population Dynamics.

Molecular biology has changed dramatically over the past two decades. Until the early 1990s genes were studied one at a time by small teams of researchers; today entire genomes are sequenced by internationally collaborating laboratories. In the bygone gene-centered era the accumulation of data was t...

Table of Contents:

• Sequences in Space
• Optimal Pairwise Alignment
• Biological Sequences and the Exact String Matching Problem
• Fast Alignment: Genome Comparison and Database Searching
• Multiple Sequence Alignment
• Sequence Profiles and Hidden Markov Models
• Gene Prediction
• Sequences in Time
• Phylogeny
• Sequence Variation and Molecular Evolution
• Genes in Populations: Forward in Time
• Genes in Populations: Backward in Time
• Testing Evolutionary Hypotheses.