Sodium Channels, Pain, and Analgesia

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Parnham, Michael J. (Επιμελητής έκδοσης), Coward, Kevin (Επιμελητής έκδοσης), Baker, Mark D. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Basel : Birkhäuser Basel, 2005.
• Σειρά: Progress in Inflammation Research
• Θέματα: Medicine.; Neurosciences.; Pharmacology.; Pain medicine.; Cell biology.; Medicine & Public Health.; Pain Medicine.; Pharmacology/Toxicology.; Cell Biology.

Sodium channels confer excitability on neurons in nociceptive pathways and exhibit neuronal tissue specific and injury regulated expression. This volume provides recent insights into the control of expression, functioning and membrane trafficking of nervous system sodium channels and reviews why sod...

Πίνακας περιεχομένων:

• Voltage-gated sodium channels and pain associated with nerve injury and neuropathies
• Current approaches for the discovery of novel NaV channel inhibitors for the treatment of brain disorders
• Voltage-gated sodium channels and visceral pain
• The functional interaction of accessory proteins and voltage-gated sodium channels
• Sodium channels and nociceptive nerve endings
• Signalling cascades that modulate the activity of sodium channels in sensory neurons
• NaV1.8 as a drug target for pain
• Role of voltage-gated sodium channels in oral and craniofacial pain
• Sodium channel gating and drug blockade
• Future directions in sodium channel research.