Advances in Targeted Cancer Therapy

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Herrling, Paul L. (Επιμελητής έκδοσης), Matter, Alex (Επιμελητής έκδοσης), Schultz, Richard M. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Basel : Birkhäuser Basel, 2005.
• Σειρά: Progress in Drug Research ; 63
• Θέματα: Medicine.; Cancer research.; Molecular biology.; Biomedicine.; Cancer Research.; Molecular Medicine.

There have been tremendous advances in our understanding of molecular and tumor biology during the past few years. In the field of cancer therapeutics, it is expected that cytotoxic drug approaches will be gradually replaced with treatments based on biological targeted approaches. Hopefully these ne...

Πίνακας περιεχομένων:

• Dawn of a new era in molecular cancer therapeutics
• Obtacles and opportunities in the clinical development of targeted therapeutics
• Tumor models for preclinical development of targeted agents
• Angiogenesis inhibitors: What is the clinical future?
• Epidermal growth factor receptor (EGFR) inhibitors in cancer therapy
• Cell survival signaling during apoptosis: Implications in drug resistance and anti-cancer therapeutic development
• Targeted histone deacetylase inhibition for cancer prevention and therapy
• Inhibitors of cyclin-dependent kinase modulators for cancer therapy
• Targeting cyclooxygenase-2 for cancer prevention and treatment
• Antisense approaches in drug discovery and development
• Preclinical development of Alimta™ (Pemetrexed, LY231514), a multitargeted antifolate.