NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders: from Genes to Therapeutics

The NPY-family of peptides encompasses several groups of neurotransmitters and hormones, which exert diverse biological and pathological actions that bear on all major vital systems. This book is a unique compilation of the most recent breakthroughs in NPY/PYY neurobiology, cardiovascular and metabo...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Zukowska, Zofia (Επιμελητής έκδοσης), Feuerstein, Giora Z. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Basel : Birkhäuser Basel, 2006.
Σειρά:Experientia Supplementum ; 95
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • NPY family of peptides in neurobiology, cardiovascular system and metabolism: genes, diseases and therapeutics
  • NPY family of peptides, receptors and processing enzymes
  • An overview of neuropeptide Y: pharmacology to molecular biology and receptor localization
  • Molecular ligand-receptor interaction of the NPY/PP peptide family
  • Physiological and pathophysiological perspectives of the NPY family of peptides
  • Modulator role of neuropeptide Y in human vascular sympathetic neuroeffector junctions
  • NPY and NPY receptors: presence, distribution and roles in the regulation of the endocardial endothelium and cardiac function
  • Neuropeptide Y and sympathetic control of vascular tone in hypertension
  • Neuropeptide Y and the cerebral circulation
  • Neuropeptide Y and the heart: implication for myocardial infarction and heart failure
  • Role of neuropeptide Y in the regulation of kidney function
  • NPY and neuron-adipocyte interactions in the regulation of metabolism
  • NPY and energy homeostasis: an opportunity for novel anti-obesity therapies
  • Subjugation of hypothalamic NPY and cohorts with central leptin gene therapy alleviates dyslipidemia, insulin resistance, and obesity for life-time
  • NPY and bone
  • NPY in alcoholism and psychiatric disorders
  • Plasticity of neuropeptide Y in the dentate gyrus after seizures, and its relevance to seizure-induced neurogenesis
  • NPY and extreme stress: lessons learned from posttraumatic stress disorder
  • NPY and chronic neurodegenerative disease
  • Genetics of the NPY family of peptides and their receptors
  • Human NPY gene variants in cardiovascular and metabolic diseases
  • Summary
  • Future directions and perspectives for therapies based on the NPY family of peptides.