Pharmacotherapy of Obesity

• Corporate Author: SpringerLink (Online service)
• Other Authors: Wilding, John P. H. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Basel : Birkhäuser Basel, 2008.
• Series: Milestones in Drug Therapy
• Subjects: Medicine.; Pharmacology.; Cardiology.; Diabetes.; Metabolic diseases.; Cell biology.; Biomedicine.; Pharmacology/Toxicology.; Metabolic Diseases.; Cell Biology.

Obesity has become a major epidemic that now rivals smoking as a risk to public health. The ensuing epidemics of diabetes, vascular disease and other complications are set to overwhelm the healthcare systems of wealthy and poorer nations alike. The need for effective pharmacotherapy has never been g...

Table of Contents:

• Why drugs?
• Some historical aspects of drug treatment for obesity
• Regulation of energy balance — towards rational drug design in obesity
• Intestinal lipase inhibitors
• Sibutramine
• The endocannabinoid system as a target for obesity treatment
• Using the body’s natural signals — gut hormones
• Influencing energy expenditure and substrate utilisation.