The NPY Family of Peptides in Immune Disorders, Inflammation, Angiogenesis and Cancer

Recent research indicates that the immune system and inflammatory reactions are governed and regulated by powerful neuronal mediators derived from the central and peripheral nervous system. The NPY family of peptides is a diverse group of neuropeptides that acts via multiple receptors, Y1-Y5, which...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Zukowska, Zofia (Επιμελητής έκδοσης), Feuerstein, Giora Z. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Basel : Birkhäuser Basel, 2005.
Σειρά:Progress in Inflammation Research
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
LEADER 04015nam a22005175i 4500
001 978-3-7643-7427-3
003 DE-He213
005 20151031001102.0
007 cr nn 008mamaa
008 100301s2005 sz | s |||| 0|eng d
020 |a 9783764374273  |9 978-3-7643-7427-3 
024 7 |a 10.1007/3-7643-7427-6  |2 doi 
040 |d GrThAP 
050 4 |a QR180-189.5 
072 7 |a MJCM  |2 bicssc 
072 7 |a MED044000  |2 bisacsh 
082 0 4 |a 616.079  |2 23 
245 1 4 |a The NPY Family of Peptides in Immune Disorders, Inflammation, Angiogenesis and Cancer  |h [electronic resource] /  |c edited by Zofia Zukowska, Giora Z. Feuerstein. 
264 1 |a Basel :  |b Birkhäuser Basel,  |c 2005. 
300 |a XV, 260 p.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
490 1 |a Progress in Inflammation Research 
505 0 |a Biology of the NPY family of peptides, their receptors and processing enzymes -- Evolutionary perspective on the NPY-PYY-PP peptides and their receptors -- Function, distribution and molecular pharmacology of NPY-family receptors -- NPY processing in neuronal and non-neuronal tissues by proconvertases -- Dipeptidyl-peptidase IV and aminopeptidase P: molecular switches of NPY/PYY receptor affinities -- The NPY family of peptides in immune disorders and inflammation -- NPY, NPY receptors and DPPIV in innate immunity and autoimmune disorders -- NPY and phagocytic cell functions -- NPY in allergic and respiratory disorders -- NPY analgesia: moving from acute to chronic pain -- The NPY family of peptides and angiogenesis -- NPY as a mediator of neurogenic angiogenesis and revascularization of ischemic tissues -- NPY-induced angiogenesis in retinopathy and wound healing -- NPY in vascular inflammation, remodeling and atherosclerosis -- The NPY family of peptides as growth factors in neurodegenerative diseases and tumor biology -- NPY as a pleiotropic growth factor -- NPY and Hippocampal Neurogenesis -- NPY family of peptides in neural crest-derived tumors -- NPY family of peptides in endocrine, breast and prostate tumors -- Summary -- Future directions and therapeutic perspectives for NPY/PYYbased anti-inflammatory and tumor suppressor drugs. 
520 |a Recent research indicates that the immune system and inflammatory reactions are governed and regulated by powerful neuronal mediators derived from the central and peripheral nervous system. The NPY family of peptides is a diverse group of neuropeptides that acts via multiple receptors, Y1-Y5, which are widespread not only in neurons but also in a variety of non-neural and immune cells. These peptides have been known as important regulators of many essential systems, such as blood pressure and cardiac function, food consumption and energy homeostasis. However, in recent years, they have also become recognized for their role as potent modulators of cell growth and immune functions with broad implications in chronic inflammatory diseases, cancer and angiogenesis. In this book, experts in the field analyze recent evidence supporting the role of NPY family of peptides in regulation of the immune/inflammatory system with special reference to its medical and therapeutic implications. 
650 0 |a Medicine. 
650 0 |a Cancer research. 
650 0 |a Immunology. 
650 0 |a Cell biology. 
650 0 |a Neurobiology. 
650 1 4 |a Biomedicine. 
650 2 4 |a Immunology. 
650 2 4 |a Cell Biology. 
650 2 4 |a Neurobiology. 
650 2 4 |a Cancer Research. 
700 1 |a Zukowska, Zofia.  |e editor. 
700 1 |a Feuerstein, Giora Z.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
776 0 8 |i Printed edition:  |z 9783764371593 
830 0 |a Progress in Inflammation Research 
856 4 0 |u http://dx.doi.org/10.1007/3-7643-7427-6  |z Full Text via HEAL-Link 
912 |a ZDB-2-SBL 
950 |a Biomedical and Life Sciences (Springer-11642)