Complement and Kidney Disease

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Zipfel, Peter F. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Basel : Birkhäuser Basel, 2006.
• Σειρά: Progress in Inflammation Research
• Θέματα: Medicine.; Human physiology.; Immunology.; Medical microbiology.; Internal medicine.; Nephrology.; Cell biology.; Biomedicine.; Cell Biology.; Human Physiology.; Internal Medicine.; Medical Microbiology.

It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement...

Πίνακας περιεχομένων:

• The complement system in renal diseases
• Complement in renal transplantation
• C1q and the glomerulonephritides: therapeutic approaches for the treatment of complement-mediated kidney diseases
• Complement deficient mice as model systems for kidney diseases
• Non-Shiga toxin-associated hemolytic uremic syndrome
• Role of complement and Factor H in hemolytic uremic syndrome
• Genetic testing in atypical HUS and the role of membrane cofactor protein (MCP; CD46) and Factor I
• Towards a new classification of hemolytic uremic syndrome
• Therapeutic strategies for atypical and recurrent hemolytic uremic syndromes (HUS)
• Complement defects in children which result in kidney diseases: diagnosis and therapy
• The role of complement in membranoproliferative glomerulonephritis
• The experience of a patient advocacy group.