Systems Biological Approaches in Infectious Diseases
Systems biology is an emerging discipline that studies the underlying network structure and the dynamics of metabolism, cells or whole organisms. It aims to investigate all interacting components simultaneously and requires data from high throughput techniques. These data from the "omic" s...
| Συγγραφή απο Οργανισμό/Αρχή: | |
|---|---|
| Άλλοι συγγραφείς: | , |
| Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Basel :
Birkhäuser Basel,
2007.
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| Σειρά: | Progress in Drug Research ;
64 |
| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Systems biology and its impact on anti-infective drug development
- Applications of transcriptional profiling in antibiotics discovery and development
- Chemical genetics: An evolving toolbox for target identification and lead optimization
- Proteomic profiling of cellular stresses in Bacillus subtilis reveals cellular networks and assists in elucidating antibiotic mechanisms of action
- Elucidating the mode-of-action of compounds from metabolite profiling studies
- A subsystems-based approach to the identification of drug targets in bacterial pathogens
- Metabolic control analysis to identify optimal drug targets
- The protein network as a tool for finding novel drug targets
- Toxicogenomics applied to predictive and exploratory toxicology for the safety assessment of new chemical entities: a long road with deep potholes
- Biological robustness in complex host-pathogen systems
- Toward whole cell modeling and simulation: Comprehensive functional genomics through the constraint-based approach
- Genomics of host-pathogen interactions.
