Adhesion Molecules: Function and Inhibition

Inflammatory cell recruitment requires the concerted action of at least five major sets of adhesion molecules: integrins, immunoglobulin-like molecules, selectins, carbohydrate structures serving as selectin ligands, and certain ectoenzymes. This volume gives a comprehensive overview on the most rel...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Ley, Klaus (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Basel : Birkhäuser Basel, 2007.
Σειρά:Progress in Inflammation Research
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Capture and rolling
  • P-selectin glycoprotein ligand-1 (PSGL-1)
  • L-selectin-mediated leukocyte adhesion and migration
  • P- and E-selectin
  • Firm adhesion
  • Endothelial ICAM-1 functions in adhesion and signaling during leukocyte recruitment
  • ?4-integrins: structure, function and secrets
  • VCAM-1 and its functions in development and inflammatory diseases
  • Lymphocyte function-associated antigen-1 (LFA-1) and macrophage antigen-1 (Mac-1): Cooperative partners in leukocyte emigration and function
  • Transendothelial migration
  • PECAM: Regulating the start of diapedesis
  • Role of ?6?1 integrin in leukocyte adhesion and transmigration
  • Vascular adhesion protein-1 (VAP-1)
  • The role of endothelial cell-selective adhesion molecule (ESAM) in neutrophil emigration into inflamed tissues
  • Structure and function of JAM proteins
  • Promises and limitations of targeting adhesion molecules for therapy.