Molecular, Clinical and Environmental Toxicology Volume 1: Molecular Toxicology /

Molecular Toxicology is the first volume of a three-volume set Molecular, Clinical and Environmental Toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals in daily life. By providing intriguing insights far down to the molecular level, t...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Luch, Andreas (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Basel : Birkhäuser Basel, 2009.
Σειρά:Experientia Supplementum, 99
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Historical milestones and discoveries that shaped the toxicology sciences
  • Physiologically based toxicokinetic models and their application in human exposure and internal dose assessment
  • The role of biotransformation and bioactivation in toxicity
  • Genotoxicity: damage to DNA and its consequences
  • Role of DNA repair in the protection against genotoxic stress
  • On the impact of the molecule structure in chemical carcinogenesis
  • Chemical induced alterations in p53 signaling
  • Molecular pathways involved in cell death after chemically induced DNA damage
  • The aryl hydrocarbon receptor at the crossroads of multiple signaling pathways
  • Mapping the epigenome — impact for toxicology
  • Receptors mediating toxicity and their involvement in endocrine disruption
  • Toxicogenomics: transcription profiling for toxicology assessment
  • The role of toxicoproteomics in assessing organ specific toxicity
  • High-throughput screening for analysis of in vitro toxicity.