The Network Collective Rise and Fall of a Scientific Paradigm /

• Κύριος συγγραφέας: Eichmann, Klaus (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Basel : Birkhäuser Basel, 2008.
• Θέματα: Life sciences.; Life Sciences.; Life Sciences, general.

The network paradigm dominated immunological research from the early 1970s to the late 1980s. The originator, Niels Jerne, hypothesized that the vast diversity of antibodies in each individual forms a network of mutual "idiotypic" recognition, thus regulating the immune system. In context...

Πίνακας περιεχομένων:

• Autobiographical note
• Autobiographical note
• Scientific Knowledge, Delusive or Deductive
• Realism, constructivism, and the naiveté of the experimental scientist
• Beyond underdeterminism: Popper, Kuhn, et al.
• The anthropology of science: Ludwik Fleck et al.
• The science wars
• Origins, Rise, and Fall of the Network Paradigm
• The immune system, pre-network paradigms
• The necessity for an interactive theory of immunity
• Proto-ideas of the network theory: antibody self-regulation, idiotypy, the brain analogy, and cybernetics
• The idiotypic network theory
• The T cell receptor puzzle
• Suppression turned idiotypic
• Network mannerism
• Post-network immunology: Idiotypic network continues at the bedside
• Hindsight
• Science between Fact and Fiction
• The fictional nature of scientific notions
• Fiction turned fact: The case of antibodies
• The enticing network: Fiction forever
• Logic and laws in life science.