Matrix Metalloproteinases in Tissue Remodelling and Inflammation

• Corporate Author: SpringerLink (Online service)
• Other Authors: Lagente, Vincent (Editor), Boichot, Elisabeth (Editor)
• Format: Electronic eBook
• Language: English
• Published: Basel : Birkhäuser Basel, 2008.
• Series: Progress in Inflammation Research
• Subjects: Medicine.; Immunology.; Pharmacology.; Infectious diseases.; Respiratory organs > Diseases.; Cell biology.; Biomedicine.; Pneumology/Respiratory System.; Infectious Diseases.; Pharmacology/Toxicology.; Cell Biology.

Matrix metalloproteinases (MMPs) are proteolytic enzymes believed to be involved in many physiological and pathological processes associated with inflammatory reactions. MMP synthesis and functions are regulated by three major mechanisms including transcriptional activation, post-transcriptional pro...

Table of Contents:

• The role of MMPs in the inflammatory process of acute lung injury
• Matrix metalloproteinases in airways inflammation of asthma and chronic obstructive pulmonary disease
• Role of matrix metalloproteases in pulmonary fibrosis
• Anti-inflammatory properties of MMP inhibitors in experimental models of chronic obstructive pulmonary disease and lung inflammation
• Role of matrix metalloproteinases (MMPs) in cystic fibrosis
• MMPs, inflammation and pulmonary arterial hypertension
• MMP roles in the initiation and progression of cardiac remodeling leading to congestive heart failure
• Matrix metalloproteinases and inflammatory diseases of the central nervous system
• Extracellular matrix remodelling and matrix metalloproteinases in the liver.