Aromatase Inhibitors

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Furr, Barrington J. A. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Basel : Birkhäuser Basel, 2008.
• Έκδοση: 2nd revised edition.
• Σειρά: Milestones in Drug Therapy
• Θέματα: Medicine.; Cancer research.; Pharmacology.; Internal medicine.; Oncology.; Cell biology.; Biomedicine.; Cancer Research.; Pharmacology/Toxicology.; Internal Medicine.; Cell Biology.

Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or action. The inhibition of oestr...

Πίνακας περιεχομένων:

• Background and development of aromatase inhibitors
• Aromatase inhibitors and models for breast cancer
• Clinical pharmacology of aromatase inhibitors
• Clinical studies with exemestane
• Clinical studies with letrozole
• Clinical studies with anastrozole
• The third-generation aromatase inhibitors: a clinical overview
• Lessons from the ArKO mouse
• Possible additional therapeutic uses of aromatase inhibitors.