Erythropoietins, Erythropoietic Factors, and Erythropoiesis Molecular, Cellular, Preclinical, and Clinical Biology /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Elliott, Steven G. (Επιμελητής έκδοσης), Foote, Mary Ann (Επιμελητής έκδοσης), Molineux, Graham (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Basel : Birkhäuser Basel, 2009.
• Έκδοση: 2nd Revised and Extended Edition.
• Σειρά: Milestones in Drug Therapy
• Θέματα: Medicine.; Pharmacology.; Endocrinology.; Sports medicine.; Cell biology.; Biomedicine.; Pharmacology/Toxicology.; Cell Biology.; Sports Medicine.

This second edition is a one-source guide to current information about red blood cell physiology and the action of native and recombinant human erythropoietic factors. Topics in the fields of erythropoiesis, recombinant protein discovery and production, and treatment of patients with anemia due to r...

Πίνακας περιεχομένων:

• Background
• Erythropoiesis: an overview
• Regulation of endogenous erythropoietin production
• Biology of erythropoietin
• Erythropoiesis—genetic abnormalities
• Erythropoiesis-stimulating agents
• Studies of erythropoiesis and the discovery and cloning of recombinant human erythropoietin
• Commercial production of recombinant erythropoietins
• Biosimilar epoetins
• New molecules and formulations
• Erythropoietin receptor
• Structural basis for the signal transduction of erythropoietin
• Intracellular signaling by the erythropoietin receptor
• Mechanism of erythropoietin receptor activation
• Clinical utility
• Pharmacokinetics of erythropoiesis-stimulating agents
• Use of erythropoietic stimulating agents in the setting of renal disease
• Abuse of recombinant erythropoietins and blood products by athletes
• Role and regulation of iron metabolism in erythropoiesis and disease
• Nonhematopoietic effects of erythropoiesis-stimulating agents.