The Hygiene Hypothesis and Darwinian Medicine

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Rook, Graham A. W. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Basel : Birkhäuser Basel, 2009.
• Σειρά: Progress in Inflammation Research
• Θέματα: Medicine.; Immunology.; Medical microbiology.; Infectious diseases.; Cell biology.; Biomedicine.; Infectious Diseases.; Medical Microbiology.; Cell Biology.

Man has moved rapidly from the hunter-gatherer environment to the living conditions of the rich industrialised countries. The hygiene hypothesis suggests that the resulting changed and reduced pattern of exposure to micro-organisms has led to disordered regulation of the immune system, and hence to...

Πίνακας περιεχομένων:

• Introduction: The changing microbial environment, Darwinian medicine and the hygiene hypothesis
• The paleolithic disease-scape, the hygiene hypothesis, and the second epidemiological transition
• Immunoregulation by microbes and parasites in the control of allergy and autoimmunity
• Hepatitis A virus, TIM-1 and allergy
• Linking lifestyle with microbiota and risk of chronic inflammatory disorders
• Soil bacteria, nitrite and the skin
• The hygiene hypothesis and allergic disorders
• Multiple sclerosis
• Inflammatory bowel disease and the hygiene hypothesis: an argument for the role of helminths
• The hygiene hypothesis and Type 1 diabetes
• The hygiene hypothesis and affective and anxiety disorders
• Immune regulation in atherosclerosis and the hygiene hypothesis
• The ‘delayed infection’ (aka ‘hygiene’) hypothesis for childhood leukaemia
• Is there room for Darwinian medicine and the hygiene hypothesis in Alzheimer pathogenesis?
• Alternative and additional mechanisms to the hygiene hypothesis.