Influenza Virus Sialidase - A Drug Discovery Target

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Itzstein, Mark von (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Basel : Springer Basel, 2012.
• Σειρά: Milestones in Drug Therapy
• Θέματα: Medicine.; Immunology.; Pharmacology.; Virology.; Infectious diseases.; Biomedicine.; Pharmacology/Toxicology.; Infectious Diseases.

Influenza continues to be an ongoing problem despite the existence of vaccines and drugs. Disease outbreaks can occur relatively quickly as witnessed with the recent emergence of the influenza virus A/H1N1 pandemic. The development of new anti-influenza drugs is thus a major challenge. This volume d...

Πίνακας περιεχομένων:

• Influenza Virus Virology
• Investigating the interaction between influenza and sialic acid – making and breaking the link
• Enzymology of Influenza Virus Sialidase
• Influenza Virus Sialidase and Structure-Based Drug Design
• The Development of Carbohydrate-based Influenza Virus Sialidase Inhibitors
• The Development of Non-carbohydrate-based Influenza Virus Sialidase Inhibitors
• Clinical Experience with Influenza Virus Sialidase Inhibitors
• Resistance Development to Influenza Virus Sialidase Inhibitors.