Non-viral Gene Therapy Gene Design and Delivery /

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Taira, Kazunari (Επιμελητής έκδοσης), Kataoka, Kazunori (Επιμελητής έκδοσης), Niidome, Takuro (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Tokyo : Springer Tokyo, 2005.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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245 1 0 |a Non-viral Gene Therapy  |h [electronic resource] :  |b Gene Design and Delivery /  |c edited by Kazunari Taira, Kazunori Kataoka, Takuro Niidome. 
264 1 |a Tokyo :  |b Springer Tokyo,  |c 2005. 
300 |a XII, 487 p.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
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505 0 |a Molecules for Gene Therapy -- Recent Progress in Non-viral Gene Delivery -- Physical Chemistry of DNA-Carrier Complexes -- Liposomes -- Polymeric Gene Carriers -- Development of a Supramolecular Nanocarrier for Gene Delivery Based on Cationic Block Copolymers -- Chitosan -- Dendrimers as DNA Carriers -- Use of Synthetic Peptides for Non-viral Gene Delivery -- An Oligonucleotide Carrier Based on ?-1,3-Glucans -- Biological and Chemical Hybrid Vectors -- Controlled Gene Delivery -- Pharmacokinetics of Gene Delivery in Cells -- Active DNA Release from Complexes -- Controlled Release of DNA Using Thermoresponsive Polymers -- Active Transport of Exogenous Genes into the Nucleus -- Controlled Intracellular Localization of Oligonucleotides by Chemical Conjugation -- Functional Nucleotide Sequences Capable of Promoting Non-viral Genetic Transfer -- Shielding of Cationic Charge of the DNA Complex to Avoid Nonspecific Interactions for In Vivo Gene Delivery -- In Vivo Gene Transfer by Ligand-Modified Gene Carriers -- Optimizing Polyplexes into Synthetic Viruses for Tumor-Targeted Gene Therapy -- Gene Transfer and Target Diseases -- Clinical Trials Using Non-viral Gene Delivery Systems -- Current Protocols of Gene Delivery -- Evaluation of Size and Zeta Potential of DNA/Carrier Complexes -- Observation of DNA/Carrier Complexes Under Fluorescence Microscopy -- Synthesis of Chemically Modified Chitosan and a Study of Its Gene Transfection Efficiency -- Newly Designed DNA Fragments for Gene Correction -- Evaluation of Gene Expression In Vivo After Intravenous and Intraportal Administration of Lipoplexes -- Evaluation by Southern Blot Hybridization of DNA Administered with a Gene Carrier to Organs -- Evaluation of the Immune Response After Administration of Plasmid DNA-Non-viral Vector Complexes -- Gateway RNAi -- Design of Genes Based on Current RNA Technology -- Design of Intracellularly Active Ribozymes and siRNAs -- RNAi-Based Inhibition Specific for Mutant Alleles in Autosomal Dominant Diseases: Sequence-Dependent and -Independent Discrimination of Mutant and Wild-Type Alleles by siRNA -- In Vivo RNA Interference: Another Tool in the Box? -- Suppression of Gene Expression via Chromatin Remodeling and the siRNA-Induced Silencing of Transcription -- Intracellular Delivery of Nucleic Acids: Differences Between Transfection and siFection Reflect Differences Between DNA and RNA, and Between Oligodeoxynucleotides and Oligonucleotides -- In Vivo Antitumor Activity of a New Cationic Liposome siRNA Complex -- Enhancing RNAi with Synthetic RNA Duplexes. 
650 0 |a Life sciences. 
650 0 |a Molecular biology. 
650 0 |a Biotechnology. 
650 0 |a Biochemical engineering. 
650 0 |a Genetic engineering. 
650 0 |a Medical biochemistry. 
650 0 |a Cell biology. 
650 1 4 |a Life Sciences. 
650 2 4 |a Cell Biology. 
650 2 4 |a Biotechnology. 
650 2 4 |a Molecular Medicine. 
650 2 4 |a Genetic Engineering. 
650 2 4 |a Biochemical Engineering. 
650 2 4 |a Medical Biochemistry. 
700 1 |a Taira, Kazunari.  |e editor. 
700 1 |a Kataoka, Kazunori.  |e editor. 
700 1 |a Niidome, Takuro.  |e editor. 
710 2 |a SpringerLink (Online service) 
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776 0 8 |i Printed edition:  |z 9784431251224 
856 4 0 |u http://dx.doi.org/10.1007/4-431-27879-6  |z Full Text via HEAL-Link 
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950 |a Biomedical and Life Sciences (Springer-11642)