Fifty Years of Cytochrome P450 Research
This book encompasses major progress and future directions in cytochrome P450 (P450) research. Included are contributions by pioneers in the discovery of P450, with chapters on the molecular and functional properties of P450 and cutting-edge applications knowledge from various fields. P450 research...
| Συγγραφή απο Οργανισμό/Αρχή: | |
|---|---|
| Άλλοι συγγραφείς: | |
| Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Tokyo :
Springer Japan : Imprint: Springer,
2014.
|
| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Preface
- Part 1 Cytochrome P450 History
- 1 Pioneers in the Early Years of Cytochrome P450 Research
- 2 Fifty Years of Progress in Drug Metabolism and Toxicology: What Do We Still Need to Know About Cytochrome P450 Enzymes?
- 3 Fifty Years of Cytochrome P450 Research: Examples of What We Know and Don’t Know
- Part 2 Structure, Function, and Practical Applications of P450
- 4 Cytochrome P450 Dynamics
- 5 Structural and Functional Diversity of Cytochrome P450
- 6 Oxygenation of Non native Substrates Using a Malfunction State of Cytochrome P450s
- 7 Plant Cytochrome P450s in Triterpenoid Biosynthesis: Diversity and Application to Combinatorial Biosynthesis
- 8 Mammalian and Bacterial Cytochromes P450 Involved in Steroid Hydroxylation: Regulation of Catalysis and Selectivity and Potential Applications
- 9 Neurosteroids: Regional Steroidogenesis
- 10 Whole Cell-Dependent Biosynthesis of Drug Metabolites Using Genetically Engineered Budding Yeast
- 11 Metabolic Diversity and Cytochromes P450 of Fungi
- 12 Metabolic Engineering of Flower Colour Pathways Using Cytochromes P450
- Part 3 Gene Regulation of P450
- 13 Aryl Hydrocarbon Receptor Suppresses Cecal Carcinogenesis
- 14 Epidermal Growth Factor Receptor: The Phenobarbital Receptor That Elicits CAR Activation Signal for P450 Induction
- 15 Steroidogenic Cytochrome P450 Gene CYP11A1: Functions and Regulation
- 16 Cooperative Regulation of Expression of Cytochrome P450 Enzymes by Aryl Hydrocarbon Receptor and Vitamin D Receptor
- Part 4 Drug Metabolism
- 17 Species, Ethnic and Individual Differences in Human Drug-Metabolizing Cytochrome P450 Enzymes
- 18 Cytochrome P450-Depedent Change in UDP- Glucuronosyltransferase Function and Its Reverse Regulation
- 19 Control of Xeno/Endobiotics-Metabolizing Cytochrome P450s by Micro RNAs
- 20 The Pharmacogenomics of Cytochrome P450s: From Molecular to Clinical Application
- 21 Cytochrome P450 Polymorphisms of Clinical Importance
- BM Epilogue
- Index.
