Protein Modifications in Pathogenic Dysregulation of Signaling
This book is devoted to recent advances in analysis of the molecular basis and dynamics of post-translational modifications (PTMs) of proteins for a comprehensive understanding of their key roles in cell signaling networks and diverse biological processes, and their perturbation in a variety of life...
| Συγγραφή απο Οργανισμό/Αρχή: | |
|---|---|
| Άλλοι συγγραφείς: | , |
| Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Tokyo :
Springer Japan : Imprint: Springer,
2015.
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| Έκδοση: | 1st ed. 2015. |
| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Preface
- Part I Novel Analytical Procedures for Signal Transduction
- 1 Phosphoproteomics-based Network Analysis of Cancer Cell Signaling Systems (Hiroko Kozuka-Hata and Masaaki Oyama)
- 2 Phos-tag-based Affinity Chromatography Techniques for Enrichment of the Phosphoproteome (Eiji Kinoshita, Emiko Kinoshita-Kikuta, and Tohru Koike)
- 3 Visualization of Intracellular Signaling with Fluorescence Resonance Energy Transfer-based Biosensors (Kazuhiro Aoki)
- 4 Technology of Wheat Cell-free Based Protein Array for Biochemical Analyses of Protein Kinases and Ubiquitin E3 Ligases (Hirotaka Takahashi, Keiichirou Nemoto, Ramadan Abdelaziz, Atsushi Uematsu, and Tatsuya Sawasaki)
- Part II Mathematical Simulation of Signal Transduction
- 5 Potential Roles of Spatial Parameters in the Regulation of NF-κB Oscillations, as Revealed by Computer Simulations (Daisuke Ohshima, Jun-ichiro Inoue, and Kazuhisa Ichikawa)
- 6 Stochastic Simulation of Stress Granules (Daisuke Ohshima, Kyoko Arimoto-Matsuzaki, Taichiro Tomida, Mutsuhiro Takekawa, and Kazuhisa Ichikawa)
- 7 Temporal Coding of Insulin Signaling (Hiroyuki Kubota and Shinya Kuroda)
- Part III Structural Analysis of Signal Transduction
- 8 Structural Biology of Protein Post-transcriptional Modifications and Cellular Signaling (Kazuki Kato, Hiroshi Nishimasu, Ryohei Ishii, Osamu Nureki, and Ryuichiro Ishitani)
- 9 Structural Basis for the Signal Initiation by TNF and TNFR (Teruya Nakamura, Yohei Mukai, Yasuo Tsutsumi, and Yuriko Yamagata)
- 10 Regulation of NF-κB Pathway by Linkage-specific Ubiquitin-binding Domains (Yusuke Sato)
- Part IV Regulation of Signal Transduction by Post-translational Modifications and Its Pathogenic Dysregulation
- 11 NF-κB Signaling and Lymphoid Malignancies (Shoji Yamaoka)
- 12 Ubiquitination-mediated NF-κB Regulation in Inflammatory Response (Fuminori Tokunaga)
- 13 NF-κB Signaling in Osteoclastogenesis (Yuu Taguchi, Jin Gohda, and Jun-ichiro Inoue)
- 14 Mitogen-activated Protein Kinase Signaling and Cancer (Mutsuhiro Takekawa and Yuji Kubota)
- 15 Critical Roles of the AKT Substrate Girdin in Disease Initiation and Progression (Atsushi Enomoto, Liang Weng, and Masahide Takahashi)
- 16 Protein Modifications Pace the Circadian Oscillation of Biological Clocks (Hikari Yoshitane and Yoshitaka Fukada)
- 17 Keap1-Nrf2 Regulatory System and Cancer (Keiko Taguchi and Masayuki Yamamoto)
- 18 Actin Filament Formation in Myofibrils and Cell Protrusions Regulated by Signal Transduction (Takeshi Endo and Kazunori Takano)
- 19 Molecular Signaling and its Pathogenic Alterations in Neuromuscular Junction Formation and Maintenance (Ryo Ueta and Yuji Yamanashi)
- 20 Post-translational Modification of Tcf/Lef: New Insights into the Regulation of Wnt/β-catenin Signaling (Tohru Ishitani)
- BM Index.
