Dose-Finding Designs for Early-Phase Cancer Clinical Trials A Brief Guidebook to Theory and Practice /

• Κύριοι συγγραφείς: Daimon, Takashi (Συγγραφέας, http://id.loc.gov/vocabulary/relators/aut), Hirakawa, Akihiro (http://id.loc.gov/vocabulary/relators/aut), Matsui, Shigeyuki (http://id.loc.gov/vocabulary/relators/aut)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Tokyo : Springer Japan : Imprint: Springer, 2019.
• Έκδοση: 1st ed. 2019.
• Σειρά: JSS Research Series in Statistics,
• Θέματα: Statistics .; Biostatistics.; Statistics for Life Sciences, Medicine, Health Sciences.; Statistical Theory and Methods.

This book provides a comprehensive introduction to statistical methods for designing early phase dose-finding clinical trials. It will serve as a textbook or handbook for graduate students and practitioners in biostatistics and clinical investigators who are involved in designing, conducting, monito...

Πίνακας περιεχομένων:

• 1. Introduction
• 2. Dose Finding in Early Phase Clinical Trials
• 3. Rule
• Based Designs
• 4. Continual Reassessment Method Designs
• 5. Escalation with Overdose Control Designs
• 6. Decision
• Theoretic Designs
• 7. Complex Designs.