DNA Replication, Recombination, and Repair Molecular Mechanisms and Pathology /

This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences....

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Hanaoka, Fumio (Επιμελητής έκδοσης), Sugasawa, Kaoru (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Tokyo : Springer Japan : Imprint: Springer, 2016.
Έκδοση:1st ed. 2016.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Part 1 DNA Replication
  • 1 Molecular Mechanism of DNA Replication
  • 2 Characteristics of Metazoan DNA Replication Origins
  • 3 DNA Replication Timing: Temporal and Spatial Regulation of Eukaryotic DNA Replication
  • Part 2 DNA Recombination
  • 4 Mechanism of Homologous Recombination
  • 5 Regulation of Recombination by Chromatin
  • 6 Homologous Recombination During Meiosis
  • Part 3 DNA Repair
  • 7 DNA Damage Recognition and Repair in Mammalian Global Genome Nucleotide Excision Repair
  • 8 The Fanconi Anemia Pathway and Interstrand Crosslink Repair
  • 9 The Crossroads of Ubiquitination and DNA Repair: A Structural Perspective
  • Part 4 Genome Instability and Mutagenesis
  • 10 Genome Instability of Repetitive Sequence: Lesson From the Ribosomal RNA Gene Repeat
  • 11 Translesion DNA Synthesis and Damage Tolerance Pathways
  • 12 Mismatch Repair
  • 13 Non-Homologous End-Joining
  • Part 5 Chromosome Dynamics and Functions
  • 14 Centromeric Chromatin and Kinetochore Assembly in Vertebrate Cells
  • 15 CST Complex and Telomere Maintenance
  • Part 6 Cell Cycle and Checkpoints
  • 16 Signaling of DNA Replication Stress Through the ATR Checkpoint
  • 17 Spindle Assembly Checkpoint: Its Control and Aberration
  • 18 Molecular Insights Into the Regulation of Apoptosis and Cellular Senescence and Their Implications for Cancer
  • Part 7 Interplay with Transcription and Epigenetic Regulation
  • 19 DNA Replication and Histone M odification
  • 20 Establishment and Maintenance of DNA Methylation
  • 21 Active DNA Demethylation in Development, Human Disease, and Cancer
  • BM Index.