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03333nam a22004695i 4500 |
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978-4-431-56015-9 |
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DE-He213 |
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20160322125741.0 |
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cr nn 008mamaa |
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160322s2016 ja | s |||| 0|eng d |
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|a 9784431560159
|9 978-4-431-56015-9
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|a 10.1007/978-4-431-56015-9
|2 doi
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|a QR180-189.5
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|a MED044000
|2 bisacsh
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|a 616.079
|2 23
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|a C-Type Lectin Receptors in Immunity
|h [electronic resource] /
|c edited by Sho Yamasaki.
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|a 1st ed. 2016.
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|a Tokyo :
|b Springer Japan :
|b Imprint: Springer,
|c 2016.
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| 300 |
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|a VI, 215 p. 29 illus., 6 illus. in color.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
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|a text file
|b PDF
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|a Part 1 ITAM-coupled Activating Receptors -- 1 Dectin-2 in anti-microbial immunity and homeostasis -- 2 The function of Mincle as a danger sensor -- 3 The DAP12-Associated Myeloid C-type Lectin 5A (CLEC5A) -- Part 2 HemITAM-bearing Receptors -- 4 Dectin-1 (CLEC7A, BGR, CLECSF12) -- 5 DNGR-1, an F-actin-binding C-type lectin receptor involved in cross-presentation of dead cell-associated antigens by dendritic cells -- 6 C-type lectin-like receptor 2 (CLEC-2) -- Part 3 ITIM-bearing Receptors -- 7 Dendritic cell immunoreceptor (DCIR): An ITIM-harboring C-type lectin receptor -- 8 Regulation and Function of the Inhibitory C-type Lectin Clec12A/MICL -- Part 4 Other receptors and related topics -- 9 DC-SIGN in infection and immunity -- 10 LOX-1 and immunity -- 11 MGL/CD301 as a unique C-type lectin expressed on dendritic cells and macrophages -- 12 Structural aspects of C-type lectin receptors -- 13 The Ligands of C-Type Lectins.
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|a The book presents the latest findings on C-type lectin receptors, focusing on individual receptors and their signaling. In recent years there have been great advances in the understanding of the function of these receptors as a newly emerging family of pattern-recognition receptors (PRRs) for pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Comprising four parts: ITAM-coupled Activating Receptors; HemITAM-bearing Receptors; ITIM-bearing Receptors; and Other Receptors and Related Topics, this comprehensive review covers a broad range of C-type lectin receptors. The updated information on C-type lectin receptors and their ligands provided will appeal to a wide readership, from basic immunologists to physicians and surgeons. In addition, sections on novel drug development make this a valuable resource for pharmaceutical scientists.
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| 650 |
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|a Medicine.
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| 650 |
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|a Immunology.
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| 650 |
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|a Pharmaceutical technology.
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|a Biochemistry.
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|a Biomedicine.
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|a Immunology.
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| 650 |
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|a Biochemistry, general.
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| 650 |
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|a Pharmaceutical Sciences/Technology.
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| 700 |
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|a Yamasaki, Sho.
|e editor.
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| 710 |
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|a SpringerLink (Online service)
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|t Springer eBooks
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|i Printed edition:
|z 9784431560135
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| 856 |
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|u http://dx.doi.org/10.1007/978-4-431-56015-9
|z Full Text via HEAL-Link
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|a ZDB-2-SBL
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| 950 |
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|a Biomedical and Life Sciences (Springer-11642)
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