Applications of Aminoacylation Ribozymes That Recognize the 3′-end of tRNA

• Κύριος συγγραφέας: Terasaka, Naohiro (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Tokyo : Springer Japan : Imprint: Springer, 2017.
• Σειρά: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Θέματα: Chemistry.; Biotechnology.; Bioorganic chemistry.; Catalysis.; Nucleic acids.; Bioorganic Chemistry.; Nucleic Acid Chemistry.

In this thesis, applications of aminoacylation ribozymes named flexizymes are described. Flexizymes have the following unique characteristics: (i) substrate RNA is recognized by two consecutive base pairs between the 3'-end of substrate RNA and the 3'-end of the flexizyme; (ii) these base...

Πίνακας περιεχομένων:

• General introduction
• Discovery of human microRNA precursor binding to folic acid by small RNA transcriptomic SELEX
• Orthogonal ribosome-tRNAs pair by engineering of peptidyl transferase center
• General conclusion.