Drebrin From Structure and Function to Physiological and Pathological Roles /

This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as a marker of dementia in neurol...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Shirao, Tomoaki (Επιμελητής έκδοσης), Sekino, Yuko (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Tokyo : Springer Japan : Imprint: Springer, 2017.
Σειρά:Advances in Experimental Medicine and Biology, 1006
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Preface
  • Part 1 History of drebrin discovery as an general introduction
  • Chapter1. Introduction
  • Part 2 Basic information about drebrin
  • Chapter2. Molecular biology of drebrin
  • Chapter3. Biochemistry of drebrin and its binding to actin filaments
  • Chapter4. Phosphorylation and molecular structure
  • Chapter5. Biophysics of drebrin binding actin filament
  • Chapter6. Cell shape change by drebrin
  • Part 3 Drebrin in Nervous system
  • Chapter7. Localization of drebrin in nervous system: LM study
  • Chapter8. Localization of drebrin in neurons: EM study
  • Chapter9. Drebrin and spine formation
  • Chapter10. Activity-dependent change of drebrin localization
  • Chapter11. Drebrin in neurogenesis and neuronal migration
  • Chapter12. Drebrin in glia
  • Part 4 Drebrin in Dementia
  • Chapter13. Drebrin in mild cognitive impairment and Alzheimer’s disease
  • Chapter14. Amyloid beta and drebrin
  • Part 5 Drebrin-binding proteins other than actin filament
  • Chapter15. Introduction
  • Chapter16. Homer and drebrin
  • Chapter17. Spiker mediates drebrin-dependent spine formation
  • Part 6 Drebrin in non-nervous system
  • Chapter18. Drebrin in immune system
  • Chapter19. Drebrin in spermatogenesis
  • Chapter20. Drebrin in polarized cells
  • Chapter21. Drebrin-dependent stabilization of nectin for maintaining endothelial integrity
  • Chapter22. Drebrin in miogenesis
  • Part 7 Assorted data relating to drebrin
  • Chapter23. Nucleotide and animo acid sequencing of drebrins
  • Chapter24. Available antibodies
  • Chapter25. Available knockout mice
  • Chapter26. How to measure drebrin isoform by ELISA
  • Chapter27. Measurement of drebrin accumulation in the spine
  • Chapter28. FRAP analysis of drebrin in the spine.