Photoaffinity Labeling for Structural Probing Within Protein

This book covers the most up-to-date photoaffinity labeling method to tackle the key loop module involved in the binding process of a bioactive small molecule to its host protein. The book introduces rational points for preparing powerful photoaffinity probes, keys for the efficient analysis of labe...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Hatanaka, Yasumaru (Επιμελητής έκδοσης), Hashimoto, Makoto (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Tokyo : Springer Japan : Imprint: Springer, 2017.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Preface
  • Chapter 1 Multifunctional Photoprobes for Identification of Ligand Sites within Biomolecules
  • Chapter 2 Tag-Creation Approaches for Highly Efficient Profiling of Interacting Proteins and Domains
  • Chapter 3 Recent Developments in Designing Compact Biological Photoprobes
  • Chapter 4 Utilities of Anti-Ligand Antibody and Mass Spectrum to Elucidate Photolabelled Sites
  • Chapter 5 Combination of Photoaffinity Label and Site-Directed Antibody for Target Proteins
  • Chapter 6 Synthesis of diazirinyl photophore and optically pure diazirinylphenylalanines for photoaffinity labeling
  • Chapter 7 Photoreactive biomacromolecules: preparation using photoreactive units and applications for analyzing biological interfaces
  • Chapter 8 Covalently capturing protein interactions in living cells by site-specific incorporation of photo-cross-linkable amino acids
  • Chapter 9 Use of hexose photolabels to reveal the structure and function of glucose transporters
  • Chapter 10 The function of the mammalian peroxisome and analysis of the fatty acid oxidation system by photoaffinity labeling
  • Chapter 11 Photoaffinity labeling methods to explore internalization mechanisms of arginine-rich cell-penetrating peptides
  • Chapter 12 Photoaffinity Labeling in Drug Discovery Research.