Cancer Drug Delivery Systems Based on the Tumor Microenvironment

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Matsumura, Yasuhiro (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Tarin, David (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Tokyo : Springer Japan : Imprint: Springer, 2019.
• Έκδοση: 1st ed. 2019.
• Θέματα: Pharmaceutical technology.; Cancer research.; Nanoscale science.; Nanoscience.; Nanostructures.; Pharmaceutical Sciences/Technology.; Cancer Research.; Nanoscale Science and Technology.

This book proposes the importance of new systems of drug design and delivery based on cancer pathophysiology in addition to cancer molecular and cellular biology. The current studies based on molecular and cellular biology while ignoring pathophysiology and pharmacology may be leading the developmen...

Πίνακας περιεχομένων:

• Preface
• Part I Cancer pathophysiology
• 1. The Cancer Stroma and its relevance to tumor survival
• 2. Cancer and blood coagulation
• 3. Tumor Blood Vessels as targets for cancer therapy
• 4. Stromal barriers within the tumor microenvironment and obstacles to nanomedicine
• Part II Antibody drug conjugates (ADC)
• 1. Recent progress in linker technology for antibody-drug conjugates: Methods for connection and release
• 2. Preclinical studies of ADC therapy for solid tumors
• 3. ADCs on the market and in clinical development
• Part III Hybrid techniques of active and passive targeting
• 1. Micelles conjugated with a pilot molecule
• 2. Liposomes conjugated with a pilot molecule
• 3. Multifunctional Envelope-type Nano Devices (MEND) for cancer therapy
• Part IV Cancer stromal targeting (CAST) therapy and diagnosis
• 1. Principle of CAST
• 2. CAST therapy
• 3. CAST diagnosis
• Part V The Current Status of Cancer Drug Delivery Systems and Future Directions
• Index.