Pancreatic Beta Cell in Health and Disease

The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin, a key metabolic hormone, which plays a central role in the maintenance of glucose homeostasis regulating glucose uptake in muscle and adipose tissue as well as carbohydrate, fat, an...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Seino, Susumu (Επιμελητής έκδοσης), Bell, Graeme I. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Tokyo : Springer Japan, 2008.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Pancreatic Beta Cell and Insulin Biosynthesis
  • Architecture of Pancreatic Islets
  • Transcriptional Regulation of Insulin Gene Expression
  • The Biosynthesis of Insulin
  • Cell Signaling and Insulin Secretion
  • Metabolic Regulation of Insulin Secretion
  • Mechanisms of Beta-Cell Death in Diabetes
  • Ion Channels and Insulin Secretion
  • Gap Junctions and Insulin Secretion
  • Protein Kinase A-Independent Mechanism of cAMP in Insulin Secretion
  • Regulation of Insulin Granule Exocytosis
  • Mechanism of Insulin Exocytosis Analyzed by Imaging Techniques
  • Two-Photon Excitation Imaging of Insulin Exocytosis
  • Pancreatic Development and Beta-Cell Formation
  • Regulation of Beta-Cell Growth and Death
  • Beta-Cell Replication
  • Stem Cells as a Cure for Diabetes
  • Use of Extra-Pancreatic Tissues for Cell Replacement Therapy for Diabetes
  • Incretins and Beta-Cell Function
  • Molecular Biology of Gluco-Incretin Function
  • Incretins and Regulation of Insulin Secretion
  • Pancreatic Beta Cell and Disease
  • Pancreatic Islet Pathology in Type 2 Diabetes
  • Genetic Disorders of the Pancreatic Beta Cell and Diabetes (Permanent Neonatal Diabetes and Maturity-Onset Diabetes of the Young)
  • ATP-Sensitive Potassium Channels in Health and Disease
  • Glucokinase in Glucose Homeostasis, Diabetes Mellitus, Hypoglycemia, and as Drug Receptor.