Multiple Primary Malignancies

• Main Author: Renda, Andrea (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Milano : Springer Milan, 2009.
• Series: Updates in Surgery
• Subjects: Medicine.; Cancer research.; Human genetics.; Oncology.; Surgery.; Abdominal surgery.; Medicine & Public Health.; Cancer Research.; Human Genetics.; Medicine/Public Health, general.; Abdominal Surgery.

Two to three decades ago, multiple primary malignancies (MPM) were considered to be simply a clinical curiosity, with sporadic reports, mostly single case descriptions, found in the literature. While in the last few years, analyses of larger series have been published, the number of cases has still...

Table of Contents:

• Nosography
• Epidemiology: Data from Cancer Registries
• Bioinformatics in MPM: Using Decision Trees To Predict a Second Tumor Site
• Carcinogenesis
• Iatrogenic Second Tumors
• Immunodeficiency and Multiple Primary Malignancies
• Multiple Primary Malignancies and Human Papilloma Virus Infections
• The Hereditary Syndromes
• Multifocal and Multicentric Tumors
• The Cancer Spectrum Related to Hereditary and Familial Breast and Ovarian Cancers
• The Role of Genetic Predisposition and Environmental Factors in the Occurrence of Multiple Different Solid Tumors. The Experience of the University Hospital of Sienna
• “Sporadic” Colorectal Tumors in Multiple Primary Malignancies
• Multiple Primary Malignancies: “Non-codified” Associations
• Laboratory for Patients at Risk of Multiple Primary Malignancies
• Multiple Primary Malignancies: Role of Advanced Endoscopy To Identify Synchronous and Metachronous Tumors of the Digestive Tract
• Diagnostic Imaging Techniques for Synchronous Multiple Tumors
• “DNA-Guided” Therapy
• Chemoprevention
• Conclusions.