HCV Infection and Cryoglobulinemia

• Corporate Author: SpringerLink (Online service)
• Other Authors: Dammacco, Franco (Editor)
• Format: Electronic eBook
• Language: English
• Published: Milano : Springer Milan : Imprint: Springer, 2012.
• Subjects: Medicine.; Internal medicine.; Hepatology.; Infectious diseases.; Oncology.; Rheumatology.; Medicine & Public Health.; Internal Medicine.; Infectious Diseases.

In 1947, Lerner and Watson showed that the cold-precipitable proteins in serum were gammaglobulins. These “cryoglobulins” were responsible for the corresponding clinical condition “cryoglobulinemia.” Meltzer and Franklin, in 1966, provided an accurate description of the typical clinical symptoms ass...

Table of Contents:

• Hepatitis C virus infection and the role of the immune system
• Cryoglobulinemia: immunochemical characterization, serological abnormalities and histopathological changes
• Structural and genetic features, cytokines and chemokines in cryoglobulinemia
• Cellular compartments of HCV infection (and replication) - Mechanism(s) of cryoprecipitation
• Clinical manifestations of cryoglobulinemia
• HCV infection, cryoglobulinemia and non-Hodgkin’s lymphomas
• Therapy of cryoglobulinemia.