The DNA Damage Response: Implications on Cancer Formation and Treatment

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Khanna, Kum Kum (Επιμελητής έκδοσης), Shiloh, Yosef (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Dordrecht : Springer Netherlands, 2009.
• Θέματα: Medicine.; Cancer research.; Human genetics.; Immunology.; Neurosciences.; Oncology.; Biomedicine.; Cancer Research.; Human Genetics.

The book The DNA Damage Response: Implications on Cancer Formation and Treatment brings together a great collection of review articles. The articles have been written by a group of experts who have a deep knowledge of the recent advances in the fields of DNA damage signalling and repair and their im...

Πίνακας περιεχομένων:

• DNA Damage Sensing and Signaling
• Signaling at Stalled Replication Forks
• An Oncogene-Induced DNA Replication Stress Model for Cancer Development
• Cellular Responses to Oxidative Stress
• Cell Cycle Regulation and DNA Damage
• Chromatin Modifications Involved in the DNA Damage Response to Double Strand Breaks
• Telomere Metabolism and DNA Damage Response
• DNA Double Strand Break Repair: Mechanisms and Therapeutic Potential
• DNA Base Excision Repair: A Recipe for Survival
• DNA Damage Tolerance and Translesion Synthesis
• Nucleotide Excision Repair: from DNA Damage Processing to Human Disease
• Chromosomal Single-Strand Break Repair
• Mouse Models of DNA Double Strand Break Repair Deficiency and Cancer
• Cancer Biomarkers Associated with Damage Response Genes
• Linking Human RecQ Helicases to DNA Damage Response and Aging
• Single-Stranded DNA Binding Proteins Involved in Genome Maintenance
• The Fanconi anemia-BRCA Pathway and Cancer
• BRCA1 and BRCA2: Role in the DNA Damage Response, Cancer Formation and Treatment.