The calcitonin gene-related peptide family form, function and future perspectives /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Hay, Deborah L. (Editor), Dickerson, Ian M. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands, 2010.
• Subjects: Medicine.; Cancer research.; Gene expression.; Endocrinology.; Biomedicine.; Biomedicine general.; Gene Expression.; Cancer Research.

This book contains a comprehensive series of reviews on the calcitonin gene-related peptide (CGRP) family of peptides. This family of peptide hormones has a diverse and constantly expanding range of important physiologic functions, including regulation of blood calcium, vascular tension, feeding beh...

Table of Contents:

• Molecular and Functional Evolution of the Adrenomedullin Family in Vertebrates: What Do Fish Studies Tell Us?
• Ligand Binding and Activation of the CGRP Receptor
• Understanding Amylin Receptors
• The CGRP-Receptor Component Protein: A Regulator for CLR Signaling
• The Calcitonin Peptide Family: What Can We Learn from Receptor Knock Out and Transgenic Mice
• Gene Targeted Mouse Models of Adrenomedullin Signaling
• Genetic Regulation of CGRP and Its Actions
• Vascular Actions of CGRP and Adrenomedullin: Mechanisms and Potential Contribution to Inflammation in the Cutaneous Microvasculature
• Insights into the Function of Intermedin/Adrenomedullin 2
• CGRP and Adrenomedullin as Pain-Related Peptides
• Amylinergic Control of Ingestive Behaviour
• CGRP Receptor Antagonists for Migraine: Challenges and Promises
• Calcitonin Receptor Expression in Embryonic, Foetal and Adult Tissues: Developmental and Pathophysiological Implications
• Conclusions and Future Perspectives.