Apoptosome An up-and-coming therapeutical tool /

"Apoptosome" is the first book that presents a concise synthesis of recent developments in the understanding of how the activation of the cell death cascade is handled by a cytosolic signalling platform known as the apoptosome. The book also discusses how insights into the regulation of ap...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Cecconi, Francesco (Επιμελητής έκδοσης), D'Amelio, Marcello (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Dordrecht : Springer Netherlands, 2010.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Physiological and Pathological Role of Apoptosis
  • Apoptosome Structure and Regulation
  • Chemical Regulation of the Apoptosome: New Alternative Treatments for Cancer
  • Molecules That Bind a Central Protein Component of the Apoptosome, Apaf-1, and Modulate Its Activity
  • Regulation of Cell Death and Survival by RNA Interference – The Roles of miRNA and siRNA
  • Beneficial Role of Taurine Against Myocardial Apoptosis During Ischemic Injury
  • BAG3 Protein: Role in Some Neoplastic Cell Types and Identification as a Candidate Target for Therapy
  • Targeting Survivin in Cancer Therapy: Pre-clinical Studies
  • Hsp70 and Hsp27: Emerging Targets in Cancer Therapy
  • Role of the RNA-Binding Protein HuR in Apoptosis and Apoptosome Function
  • Acetylcholinesterase as a Pharmacological Target in Cancer Research
  • Putative Role of HCA66, A New Apaf-1 Interacting Protein, in the Physiopathology of NF1 Microdeletion Syndrome Patients
  • Cristae Remodeling and Mitochondrial Fragmentation: A Checkpoint for Cytochrome c Release and Apoptosis?
  • Apoptosome Pharmacological Manipulation: From Current Developments in the Laboratory to Clinical Implications
  • The Therapeutic Role of Taurine in Ischaemia-Reperfusion Injury
  • Targeting Survivin in Cancer Therapy: Clinical Considerations.