Signal Transduction in Cancer Metastasis

The poor prognosis and high mortality for cancer patients are majorly ascribed to tumor metastasis, one of the most complicated pathological processes. Elucidation of molecular mechanisms for metastasis is essential for management and prevention of this lethal condition. In the book to be published,...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Wu, Wen-Sheng (Επιμελητής έκδοσης), Hu, Chi-Tan (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Dordrecht : Springer Netherlands : Imprint: Springer, 2010.
Σειρά:Cancer Metastasis - Biology and Treatment, 15
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Overview of Signal Transduction in Tumor Metastasis
  • Microenvironment Triggers EMT, Migration and Invasion of Primary Tumor via Multiple Signal Pathways
  • The ERK1/2 MAP Kinase Signaling Pathway in Tumor Progression and Metastasis
  • Mitogen-Activated Protein Kinase-Activated Protein Kinases and Metastasis
  • Grb2 and Other Adaptor Proteins in Tumor Metastasis
  • The Role of ROS Signaling in Tumor Progression
  • Signal Cross Talks for Sustained MAPK Activation and Cell Migration Mediated by Reactive Oxygen Species: The Involvement in Tumor Progression
  • Insights into the Dynamics of Focal Adhesion Protein Trafficking in Invasive Cancer Cells and Clinical Implications
  • Notch Signaling in Cancer Metastasis
  • New Concepts on the Critical Functions of Cancer- and Metastasis-Initiating Cells in Treatment Resistance and Disease Relapse: Molecular Mechanisms, Signaling Transduction Elements and Novel Targeting Therapies
  • Involvement of Lipid Rafts in Growth Factor Receptors-Mediated Signaling for Cancer Metastasis
  • Cadherin-Catenin Signaling in Ovarian Cancer Progression
  • PTP4A3, a Signal Molecule Deregulated in Uveal Melanoma Metastasis
  • Signal Transduction Pathways Involved in Hepatocarcinogenesis and Metastasis of Hepatoma.