The Myelodysplastic Syndromes

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Várkonyi, Judit (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Dordrecht : Springer Netherlands : Imprint: Springer, 2011.
• Θέματα: Medicine.; Hematology.; Biomedicine.; Biomedicine general.; Medicine/Public Health, general.

Myelodysplastic syndromes (MDS) are the most common hematological malignancies involving mostly the elderly population. The major morbidity relates to patients’ symptomatic cytopenias.MDS was previously named as  “preleukemia “ or “ smoldering leukemia” as the lack of terminal cells in MDS and becau...

Πίνακας περιεχομένων:

• 1. PREFACE
• 2. The history of the Myelodysplastic Syndromes
• 3. Susceptibility to MDS: DNA repair and detoxification genes
• 4. Myelodysplastic syndromes/neoplasms: Morphological and Immunohistochemical features and standard evaluation
• 5. Diagnostic Criteria and Classification of Myelodysplastic Syndromes
• 6. Cytogenetics of MDS
• 7. Molecular changes in myelodysplastic syndrome
• 8. Prognostic Scoring in MDS
• 9. Flow Cytometry in Myelodysplastic Syndromes
• 10. MDS as an Autoimmune Process
• 11. The Myelodysplastic Overlap Syndromes
• 12. Iron and copper Metabolismin the Myelodysplastic Syndromes
• 13. Pathogenesis and Management of Iron Overload in MDS
• 14. Cytokines in MDS. Abnormalities and treatment
• 15. Therapeutic Modalities and new molecular targets in MDS
• 16. Haematopoietic Stem Cell Transplantation in MDS for Adults
• 17. JMML and Myelodysplastic Syndrome in children.