Tumors of the Central Nervous System, Volume 2 Gliomas: Glioblastoma (Part 2) /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Hayat, M.A (Editor)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands, 2011.
• Series: Tumors of the Central Nervous System ; 2
• Subjects: Medicine.; Cancer research.; Neuroradiology.; Oncology.; Neurosurgery.; Pathology.; Surgery.; Biomedicine.; Cancer Research.

Advantages and limitations of biomarkers in gliomagenesis are described. Molecular subtypes of gliomas are detailed. The role played by TP53 gene mutation in the deadliest brain tumor, glioblastoma multiforme, is pointed out. The role of mutations of IDH1 and IDH2, and isocitrate dehydrogenases in m...