Advances in Mitochondrial Medicine

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Scatena, Roberto (Επιμελητής έκδοσης), Bottoni, Patrizia (Επιμελητής έκδοσης), Giardina, Bruno (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Dordrecht : Springer Netherlands, 2012.
• Σειρά: Advances in Experimental Medicine and Biology, 942
• Θέματα: Medicine.; Cancer research.; Molecular biology.; Pharmacology.; Medical biochemistry.; Biomedicine.; Biomedicine general.; Cancer Research.; Molecular Medicine.; Pharmacology/Toxicology.; Medical Biochemistry.

Mitochondria are far more than the “powerhouse” of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and thermogene...

Πίνακας περιεχομένων:

• Section I – Physiology and structure of Mitochondria
• 1.               The oxidative phosphorylation system in mammalian mitochondria
• 2. Physiology and pathophysiology of mitochondrial DNA
• 3. Mitochondrial calcium as a key regulator of mitochondrial activities
• 4. Mitochondria and Nitric Oxide: Chemistry and Pathophysiology
• 5. Mitochondria and reactive oxygen species - which role in physiology and pathophysiology?
• 6. Uncoupling proteins: molecular, functional, regulatory, physiological and pathological aspects
• 7. The mitochondrial pathways of apoptosis
• Section II – Mitochondria and disease
• 8. Inherited mitochondrial disorders
• 9. Mitochondria and metabolism diseases
• 10. Mitochondria and diabetes. An intriguing pathogenetic role
• 11. Mitochondria and heart diseases
• 12. Mitochondria in neurodegeneration
• 13. Mitochondria and cancer: a growing role in apoptosis, cancer cell metabolism and dedifferentiation
• Section III – Mitochondria and Aging
• 14.Mitochondria and aging
• 15. Mitochondria and pharmacology. -16. Iatrogenic mitochondriopathies: a recent lesson from nucleoside/nucleotide reverse transcriptase inhibitors
• 17. Dysfunction of mitochondrial respiratory chain complex I in neurological disorders: genetics and pathogenetic mechanisms
• 18. Anthracyclines and mitochondria
• Section IV-  Applications of Mitochondrial science
• 19. Mitochondrial proteomics approaches for new potential diagnostic and prognostic biomarkers in cancer
• 20. Mitochondria in Anthropology and forensic medicine.  .