Mortalin Biology: Life, Stress and Death

The phrase “Life, stress and death” connects three terms, but is there a biological basis for that? Are there molecules that are essential to/or mediate these phenomena? This contributory volume “Mortalin Biology: Life, Stress and Death” is a remarkable compilation of the research outcomes on the st...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Kaul, Sunil C. (Επιμελητής έκδοσης), Wadhwa, Renu (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Dordrecht : Springer Netherlands : Imprint: Springer, 2012.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Contributors
  • Foreword
  • Preface
  • Section 1: Structure and Function of Mortalin.-  1. Birth of Mortalin: Multiple Names, Niches and Functions Connecting Stress, Senescence and Cancer.-  2. Mortalin’s Machinery.-  3. The Role of Mortalin in Iron Homeostasis .-  4. Functional Characteristics of Mortalin.- Section 2:  Mortalin in Evolution2 Deocaris.-  5.  Mortalin and Drosophila DmHsp22: Two Mitochondrial Chaperones Regulating Aging and Carcinogenesis .-  6. Mortalin in Invertebrates and The Induction of Apoptosis by Wild-Type p53 Following Defeat of Mortalin-Based Cytoplasmic Sequestration in Cancerous Clam Hemocytes  .-  7. Mortalin and Stem Cells: A Study from Planarians.-  Section 3: Mortalin in Health and Disease.-  8. Mortalin in Cell Protection from Immune Attack .-  9. Mortalin in Neurological Diseases.-  10. Loss of Mortalin Function in Parkinson’s Disease – Supporting the Mitochondrial Pathway of Neurodegeneration.-  11. Hsp75/mortalin and Protection from Ischemic Brain Injury
  • 12. Catecholamine Regulated Protein (CRP40), A Splice Variant of Mortalin-2: Functional Role in CNS Disorders.-  13. Chaperonopathies: Diseases in Which Mortalin and Other Hsp-Chaperones Play a Role in Etiology and Pathogenesis.-  Section 4:  Mortalin and Cancer.-  14. The Many Faces of Mortalin and Tid1.-  15. Mortalin: A Positive Regulator of Centrosome Duplication and Amplification.-  16. Mortalin Expression in Normal and Neoplastic Tissues .-  17. Mortalin - p53 Interaction as A Target for Liver Cancer Therapy.-  18. Mortalin Targeting Gadgets for Cancer Therapy
  • Section 5:  Mortalin Based Technologies.-  19. Cell Internalizing Anti-Mortalin Antibody for Generation of Illuminating MSCs for Long-Term in vitro and in vivo Tracking.-  20. Mortalin Staining Pattern as A Reporter for Cell Based Anti-Cancer Drug Screening.-  21. Cell Internalizing Anti-Mortalin Antibody as a Nanocarrier.