Site-directed insertion of transgenes

• Corporate Author: SpringerLink (Online service)
• Other Authors: Renault, Sylvaine (Editor), Duchateau, Philippe (Editor)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2013.
• Series: Topics in Current Genetics, 23
• Subjects: Chemistry.; Gene expression.; Gene therapy.; Medical genetics.; Genetic engineering.; Genetic Engineering.; Gene Therapy.; Gene Function.; Gene Expression.

The post-genomic era has brought new challenges and opportunities in all fields of the biology. In this context, several genome engineering technologies have emerged that will help deciphering genes function by as well as improve gene therapy strategies. Genomic modifications such as knock-in, knock...