The Eukaryotic Replisome: a Guide to Protein Structure and Function

• Corporate Author: SpringerLink (Online service)
• Other Authors: MacNeill, Stuart (Editor)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2012.
• Series: Subcellular Biochemistry, 62
• Subjects: Medicine.; Cancer research.; Biochemistry.; Nucleic acids.; Proteins.; Biomedicine.; Biomedicine general.; Biochemistry, general.; Protein Science.; Protein Structure.; Nucleic Acid Chemistry.; Cancer Research.

Successful chromosome replication is vital for maintaining the integrity of the genetic material in all forms of cellular life. In humans, there are clear links between chromosome replication defects and genome instability, genetic disease and cancer, making a detailed understanding of the molecular...