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|a 9789400747197
|9 978-94-007-4719-7
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|a 10.1007/978-94-007-4719-7
|2 doi
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|a Glioma Signaling
|h [electronic resource] /
|c edited by Jolanta Barańska.
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|a Dordrecht :
|b Springer Netherlands :
|b Imprint: Springer,
|c 2013.
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|a X, 227 p. 39 illus., 27 illus. in color.
|b online resource.
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|a text
|b txt
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|a computer
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|a online resource
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|a text file
|b PDF
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|a Advances in Experimental Medicine and Biology,
|x 0065-2598 ;
|v 986
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|a Gliomas, developing in the brain from the transformed glial cells, are a very special kind of tumors, extremely refractory to conventional treatments. Therefore, for the development of new antitumor strategies, a better understanding of molecular mechanisms responsible for their biology, growth and invasion is still needed. Glioma Signaling is a text reference on cellular signaling processes regulating gliomas physiology and invasiveness. The first half of the book is focused on the mechanism of nucleotide receptor activation by exogenous nucleotides. The remaining chapters deal with the formation of complex signaling cascades, including cytoplasmic transcription factors, induced by growth factors, cytokines and cannabinoids. The book provides a framework explaining how signal transduction elements may modulate glioma cytoskeleton structure, cytoplasmic calcium concentration, cellular growth, progression and invasion, as well as presents perspectives concerning potential targets for glioma therapy.
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|a Medicine.
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|a Cancer research.
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|a Molecular biology.
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|a Neurosciences.
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|a Biomedicine.
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|a Biomedicine general.
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|a Cancer Research.
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|a Neurosciences.
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| 650 |
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|a Molecular Medicine.
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| 700 |
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|a Barańska, Jolanta.
|e editor.
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| 710 |
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|a SpringerLink (Online service)
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|t Springer eBooks
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|i Printed edition:
|z 9789400747180
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|a Advances in Experimental Medicine and Biology,
|x 0065-2598 ;
|v 986
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|u http://dx.doi.org/10.1007/978-94-007-4719-7
|z Full Text via HEAL-Link
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|a ZDB-2-SBL
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| 950 |
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|a Biomedical and Life Sciences (Springer-11642)
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