Tetraspanins

• Corporate Author: SpringerLink (Online service)
• Other Authors: Berditchevski, Fedor (Editor), Rubinstein, Eric (Editor)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2013.
• Series: Proteins and Cell Regulation ; 9
• Subjects: Medicine.; Immunology.; Endocrinology.; Biochemistry.; Proteins.; Biomedicine.; Biomedicine general.; Protein Science.; Biochemistry, general.

Tetraspanin proteins have recently emerged as a new class of modulators of various processes involving cell surface receptors, including cell migration and invasion, host immune responses, cell-cell fusion, and viral infection. The book summarises recent advances in the fields of biology in which th...

Table of Contents:

• Foreword
• 1 Structural Bases for Tetraspanin Functions
• 2 The Evolution of Tetraspanins Through a Phylogenetic Lens
• 3 Organisation of the Tetraspanin Web
• 4 Dynamic Partitioning of Tetraspanins Within Plasma Membranes
• 5 Tetraspanins as Regulators of Protein Trafficking
• 6 The Role of Tetraspanins in Cell Migration and Intercellular Adhesion
• 7 Genetic Evidence for Tetraspanin Functions
• 8 Tetraspanins in Lower Eukaryotes
• 9 The Role of Tetraspanin Complexes in Egg-Sperm Fusion
• 10 Tetraspanins and Immunity
• 11 Tetraspanins in Cancer
• 12 Uroplakins as Unique Tetraspanin Networks
• 13 Essential Tetraspanin Functions in the Vertebrate Retina
• 14 The Role of CD81 in HCV and Plasmodium Infection
• 15 Tetraspanins as Facilitators of Viral and Cellular Information Transfer
• Index.