Heat Shock Proteins of Malaria

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Shonhai, Addmore (Επιμελητής έκδοσης), Blatch, Gregory L. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Dordrecht : Springer Netherlands : Imprint: Springer, 2014.
• Θέματα: Medicine.; Parasitology.; Infectious diseases.; Proteins.; Biomedicine.; Biomedicine general.; Protein Science.; Infectious Diseases.

This book describes the role of heat shock proteins in the life cycle of malaria parasites. The work includes a general introduction on the structural and functional features of heat shock proteins. The main focus is on the role of heat shock protein families from Plasmodium falciparum, their role i...

Πίνακας περιεχομένων:

• Introduction: The importance of molecular chaperones in survival and pathogenesis of the malaria parasite Plasmodium falciparum
• General structural and functional features of molecular chaperones
• The role of Hsp70s in the development and pathogenicity of Plasmodium species
• Role of the Hsp40 family of proteins in the survival and pathogenesis of the malaria parasite
• Role of Hsp90 in Plasmodium falciparum malaria
• The role of parasite heat shock proteins in protein trafficking and host cell remodeling
• Role of heat shock proteins in immune modulation in malaria
• Establishment of Plasmodium falciparum extracellular compartments in its host erythrocyte
• Chaperones and Proteases of Plasmodium falciparum
• Heat shock proteins as targets for novel anti-malarial drugs
• What do we know, what do we not know, and what should the future focus be?.