Mechanisms of Gene Regulation

• Κύριοι συγγραφείς: Carlberg, Carsten (Συγγραφέας), Molnár, Ferdinand (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Dordrecht : Springer Netherlands : Imprint: Springer, 2014.
• Θέματα: Medicine.; Gene expression.; Proteins.; Biomedicine.; Gene Expression.; Protein Structure.

This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of expression is a fundamental aspect of nearly...

Πίνακας περιεχομένων:

• Overview: What is gene expression?
• The impact of chromatin
• The basal transcriptional machinery
• Transcription factors
• Linking signal transduction and gene regulation
• Switching genes on and off at the example of nuclear receptors
• Mapping the genome
• Chromatin modifiers
• Genomic imprinting
• The epigenome
• Chromatin remodeling
• Chromatin architecture
• Regulatory RNA.