The Essential Guide to N-of-1 Trials in Health

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Nikles, Jane (Επιμελητής έκδοσης), Mitchell, Geoffrey (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Dordrecht : Springer Netherlands : Imprint: Springer, 2015.
• Έκδοση: 1st ed. 2015.
• Θέματα: Medicine.; Pharmacy.; Pharmacotherapy.; Statistics.; Psychology.; Biomedicine.; Biomedicine general.; Psychology, general.; Statistics for Life Sciences, Medicine, Health Sciences.

N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial d...

Πίνακας περιεχομένων:

• Preface
• Introduction
• What are N-of-1 trials?- N-of-1 trials in the behavioural sciences
• N-of-1 trials in medical contexts
• Aggregated N-of-1 trials
• Methodological considerations for N-of-1 trials
• Randomization, allocation concealment and blinding
• Data collection and quality control
• Individual reporting of N-of-1 trials to patients and clinicians
• Assessing and reporting adverse events
• Research ethics and N-of-1 trials
• Statistical analysis of N-of-1 trials
• The economics of N-of-1 trials
• Reporting N-of-1 trials to professional audiences
• Single patient open trials
• Systematic review and meta-analysis using N-of-1 trials
• Where are N-of-1 trials headed?- Index.