DNA Replication - Damage from Environmental Carcinogens

• Main Author: Zhang, Huidong (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2015.
• Series: SpringerBriefs in Biochemistry and Molecular Biology, 17
• Subjects: Life sciences.; Pharmacology.; Nucleic acids.; Cell biology.; Life Sciences.; Nucleic Acid Chemistry.; Cell Biology.; Pharmacology/Toxicology.

This book reviews the main concepts concerning DNA damage due to environmental carcinogens, the effects of DNA damage on DNA replication using a single DNA polymerase or DNA replisome, and the effects of carcinogens on various cell activities. It also introduces the detailed protocols for bypassing...

Table of Contents:

• DNA replication
• Disturbances of the DNA replication system
• Fate of DNA replisome upon encountering DNA damage
• External Causes for DNA Damage
• Effect of environmental carcinogens on cellular physiology
• Protocols for studies of bypass of DNA damage by DNA polymerase.