Admixture Dynamics, Natural Selection and Diseases in Admixed Populations

• Main Author: Jin, Wenfei (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2015.
• Edition: 1st ed. 2015.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Medicine.; Human genetics.; Bioinformatics.; Biomathematics.; Biomedicine.; Human Genetics.; Genetics and Population Dynamics.

In this thesis, Dr. Jin presents the distribution of ancestral chromosomal segments in the admixed genome, which could provide the information needed to explore population admixture dynamics. The author derives accurate population histories of African Americans and Mexicans using genome-wide single...

Table of Contents:

• Introduction
• Distribution of length of ancestral chromosomal segments in admixed genomes
• Exploring population admixture dynamics via distribution of LACS
• Genome-wide search for signatures of natural selection in African Americans
• Complex selective forces shaping the genes underlying human diseases
• Materials and Methods.