Aminoacyl-tRNA Synthetases in Biology and Medicine

• Corporate Author: SpringerLink (Online service)
• Other Authors: Kim, Sunghoon (Editor)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2014.
• Series: Topics in Current Chemistry, 344
• Subjects: Chemistry.; Medicinal chemistry.; Proteins.; Systems biology.; Biological systems.; Medicinal Chemistry.; Protein Science.; Biological Networks, Systems Biology.

1 Synthetic and Editing Mechanisms of Aminoacyl-tRNA Synthetases John J. Perona, Ita Gruic-Sovulj 2 Emergence and Evolution Tammy J. Bullwinkle, Michael Ibba 3 Architecture and Metamorphosis Min Guo, Xiang-Lei Yang 4 Protein–Protein Interactions and Multi-component Complexes of Aminoacyl-tRNA Synthe...

Table of Contents:

• Catalysis
• Emergence and Evolution
• Architecture
• Protein-protein Interactions and Multicomponent Complexes
• Interactions with RNAs
• Secretion and Circulation
• Regulatory Roles
• Neural Diseases
• Cancer
• Immune Diseases
• Pathologic Implications of Mitochondrial tRNA Synthetases
• Infectious Diseases
• Reprogramming of Genetic Code
• Novel functions of tRNAs
• Perspectives for Systems and Synthetic Bio-Medicine.